Pyrroloquinoline Quinone Acid phofo (72909-34-3) video
Pyrroloquinoline Quinone acid Slitšobotsi
| Name: | Pyrroloquinoline Quinone Acid phofo |
| CAS: | 72909-34-3 |
| Ho hloeka | 98% |
| Limolek'hule Mokgwa wa ho Nahana: | C14H6N2O8 |
| Boima ba limolek'hule: | 330.208 g / mol |
| Melt Point: | 200 ° C |
| Lebitso la k'hemik'hale | 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid |
| Li-synonyms: | PQQ ea Coenzyme
Coenzyme, PQQ Moqapi, PQQ Methoxatin PQQ Coenzyme |
| InChI Key: | MMXZSJMASHPLLR-UHFFFAOYSA-N |
| Halofo ea bophelo: | Lihora tse 3-5 |
| Solubility: | Soluble ho DMSO, Methanol, Metsi |
| Boemo ba ho Boloka: | 0 - 4 C bakeng sa nako e khuts'oane (matsatsi ho isa ho libeke), kapa -20 C nako e telele (likhoeli) |
| e sebetsa joang: | PQQ e nka karolo mesebetsing e fapaneng ea biolo ka melemo ea ho pholoha (mohlala, ts'ebetso ea kholo ea neonatal, ts'ebetso ea ho ikatisa, mesebetsi ea methapo, le mitochondriogeneis), hammoho le melemo ea ts'ebetso ea neuroprotection le mesebetsi e ntlafalitsoeng ea ts'ireletso ea mmele, ea ho itšireletsa mafung le ea antioxidant. |
| Ponahalo: | phofo e sootho e khubelu |
Pyrroloquinoline Quinone Acid phofo ke eng (72909-34-3)?
Pyrroloquinoline quinone (PQQ) phofo, coenzyme ea phepo e kang vithamini e amanang le lelapa la B-vithamine, e na le mabitso a mang a mangata a tummeng, joalo ka methoxatin, BioPQQ, joalo-joalo PQQ e fumaneha ka tlhaho lijong tsa limela tse ngata, litholoana, meroho (ka miniscule lipalo) le maemo a phahameng a lekanang a ka bonoa lihlahisoeng tse tlotsitsoeng tsa Soybea joalo ka Soybeans e tala, sepinichi, lithunthung tsa lipalesa, pepere e tala, litholoana tsa Kiwi, jj.
Melemo ea Pyrroloquinoline Quinone Acid (72909-34-3)
PQQ e sireletsa liseleng 'meleng ho tsoa ho li-oxidative senya mme e ts'ehetsa metabolism ea matla le botsofali bo phetseng hantle. E boetse e nkoa e le cofactor ea palesa e nang le ts'ebetso ea antioxidant le B ea mofuta oa B. E phahamisa bophelo bo botle ba kelello le memori ka ho loants'a ho se sebetse hantle ha methapo ea mali le ho sireletsa li-neuron ho tsoa tšenyo ea oxidative.
MAHLOMPHO MOTSE
Ntle le melemo e meraro ea mantlha e thathamisitsoeng ka holimo, PQQ e fana ka melemo e meng e fokolang, e tsebahalang. PQQ e kanna ea khothaletsa semelo sa Nerve Growth Factor (NGF), e leng se ka lebisang kholisong e ngata le pholohong. PQQ e kanna ea khona ho ntlafatsa tsoalo, leha ho ntse ho hlokahala lithuto tse ling tse ngata ho fumana sephetho se hlakileng. Melemo e meng ea ho nka PQQ e ka fumanoa ha ho etsoa lipatlisiso tse ling hape.
Pyrroloquinoline Quinone acid Mokhoa oa ts'ebetso?
Patlisiso e bonts'itse Pyrroloquinoline quinone e ts'ehetsa sebopeho le ts'ebetso ea mitochondrial e phetseng hantle ho thusa ho boloka ts'ebeliso e ntle ea kelello joalo ka ho hopola, ho hopola le ho tseba ha re ntse re tsofala:
- E ama litsela tse bonts'ang seleng tse amehang holima kholo ea lisele, phapang le pholoho
- Sireletsa li-mitochondria tse seng li le kotsing
- E thusa ho hlahisa li-mitochondria tse ncha
- Sireletsa lisele tsa methapo
Melemo ea ho nka Pyrroloquinoline quinone e tsoa mefuteng e fapaneng e fapaneng, eo kaofela e kenyang liprotheine tsa lisele. Pele, PQQ e kenya tšebetsong mokelikeli o fumanehang khubung ea lisele tse bitsoangNR1C3. Moamoheli ona oa nyutlelie o ikarabella bakeng sa ho bokella ka kakaretso, ho kenyeletsoa kholo ea sele le ho hema ha mitochondrial.
Ka mokhoa o ts'oanang le ts'ebetso ea mokotla oa CILTEP, Pyrroloquinoline quinone phofo e kenya protheine e tšoaeang CREB, e bakang ka kotloloho kholo ea mitochondria e ncha ebile e khothaletsa ho theha khokahano e ncha ea methapo, maemong a bokong. Ntle le moo, Pyrroloquinoline quinone phofo e sebetsana le limolek'hule tse 'maloa tsa ka hare tse fanang ka ts'ireletso ho khatello ea maikutlo. Sena se bohlokoa haholo bakeng sa lisele tsa boko, tse sebelisang matla a mangata mme li hlahisa li-radicals tse ngata tsa mahala ka lebaka leo.
Pyrroloquinoline Quinone acid kopo
Pyrroloquinoline quinone (PQQ), eo hape e bitsoang methoxatin, ke redox cofactor. E fumanoa mobung le lijong tse kang kiwifruit, hammoho le lebese la matsoele la motho. Li-Enzymes tse nang le Pyrroloquinoline quinone phofo li bitsoa li-quinoproteins. Glucose dehydrogenase, e 'ngoe ea li-quinoprotein, e sebelisoa e le sensor ea glucose. Pyrroloquinoline quinone phofo e hlohlelletsa kholo ea libaktheria.
Pyrroloquinoline quinone e fumanoe e ntlafatsa mohopolo o seng kapele feela, empa le mesebetsi e meng e phahameng ea boko joalo ka tlhokomeliso ea sebaka. Litholoana tsa phofo ea Pyrroloquinoline quinone li ile tsa ntlafatsoa ha ntho eo e sebelisoa le CoQ10. Melemo ea bohlokoa ea Pyrroloquinoline quinone phofo e kenyelletsa bophelo bo botle ba mitochondrial, tšehetso ea boko le bophelo bo botle ba pelo.
PQQ phofo Ho rekisoa(U ka reka Pyrroloquinoline Quinone Acid phofo ka bongata)
Khamphani ea rona e thabela likamano tsa nako e telele le bareki ba rona hobane re tsepamisa maikutlo mosebetsing oa bareki le ho fana ka lihlahisoa tse ntle. Haeba o rata sehlahisoa sa rona, re feto-fetoha le maemo ka mokhoa oo re ratang ho odara ka oona o lekanang tlhoko ea hau le nako ea hau ea kapele ea li-odara e tiisa hore o tla latsoa sehlahisoa sa rona ka nako. Re shebile hape le lits'ebeletso tse kenyellelitsoeng boleng. Re fumaneha bakeng sa lipotso tsa ts'ebeletso le tlhaiso-leseling ho ts'ehetsa khoebo ea hau.
Re le mofani oa Pyrroloquinoline Quinone Acid phofo ea phofo ka lilemo tse ngata, re fana ka lihlahisoa ka theko ea tlholisano, 'me sehlahisoa sa rona ke sa boleng bo holimo ebile sea hlahlojoa ka thata, se ikemetseng ho netefatsa hore se bolokehile bakeng sa ts'ebeliso lefatšeng ka bophara.
References
- Phala, Kelsey (12 Hlakola 2017). "Antioxidant ea Tlhaho e ka Thibela Mafu a Sebete". lehlohonolo. E khutlisitsoe ka la 14 Hlakola 2017.
- Ameyama M, Matsushita K, Shinagawa E, Hayashi M, Adachi O (1988). "Pyrroloquinoline quinone: excretion ka methylotrophs le tlhoko ea kholo bakeng sa likokoana-hloko". Li-BioFactors. 1 (1): 51–3. PMID 2855583.
- Hauge JG (1964). "Glucose dehydrogenase ea bacterial anitratum: enzyme e nang le sehlopha sa maiketsetso". J Biol Chem. 239: 3630–9. PMID 14257587.
- Pinroloquinoline Quinone
