Sesamol (533-31-3) Slitšobotsi
| Name: | Sesamol |
| CAS: | 533-31-3 |
| Ho hloeka | 98% |
| Limolek'hule Mokgwa wa ho Nahana: | C7H6O3 |
| Boima ba limolek'hule: | 138.12 g / mol |
| Melt Point: | 62 ho 65 ° C |
| Ntlha e belang: | 121 ho 127 ° C |
| Lebitso la k'hemik'hale | 1,3-Benzodioxol-5-ol 3,4- (Methylenedioxy) phenol 3,4-Methylenedioxyphenol |
| InChI Key: | LUSZGTFNYDARNI-UHFFFAOYSA-N |
| Halofo ea bophelo: | N / A |
| Solubility: | Qhibilihang ka har'a metsi |
| Boemo ba ho Boloka: | 0 - 4 C bakeng sa nako e khuts'oane (matsatsi ho isa ho libeke), kapa -20 C nako e telele (likhoeli) |
| e sebetsa joang: | Sesamol, motsoako oa phepo e nepahetseng oa phenolic antioxidant o ntlafalitsoeng ka peo ea sesame, e bonts'itsoe hore e na le mesebetsi e ka bang teng ea likokoana-hloko. |
| Ponahalo: | bosoeu bo bosoeu ho bosoasoi |
Sesamol (533-31-3) Ponahalo ea NMR
Haeba o hloka COA, MSDS, HNMR bakeng sa sehlopha ka seng sa sehlahisoa le tlhaiso-leseling e ngoe, ka kopo ikopanye le rona mookameli oa papatso.
Sesamol (533-31-3) ke eng?
Sesamol ke motsoako oa phenolic o fumanoang peo ea sesame le oli ea sesame mme o nkuoa e le karolo e kholo ea antioxidant ka har'a oli, ho thibela ho senyeha ha lioli. E kanna ea boela ea thibela tšenyo ea lioli ka ho sebetsa joalo ka sebolaya-mafu. Sesamol e qhibiliha ka mokhoa o fokolang ka metsing, empa e fosahetse ka oli e ngata.
Sesamol phofo e ntšoa ho tsoa ho peo ea Sesamol e nang le bokhoni ba ho fana ka melemo e fapaneng bakeng sa basebelisi. Phofo ena e na le li-antioxidants, tse thibelang ho senyeha ha oli ka ho sebetsa joalo ka antifungal le ho sireletsa 'mele oa hau ts'enyo ea li-radicals tsa mahala. Oli ea Sesame e sebelisoa haholo meriana ea Ayurveda ho phekola mathata a 'maloa a bophelo ntle le leha e le efe ditlamorao. Matla ana a na le lisebelisoa tse 'maloa tsa pharmacological tse kenyelletsang antioxidant, anti-inflammatory, le neuroprotective properties. Sesamol, motsoako oa phenolic antioxidant o matlafalitsoeng ka peo ea sesame, o bontšitsoe hore o na le mesebetsi e ka bang teng ea ho thibela mofetše.
Melemo ea Sesamol (533-31-3)
Surname ea antioxidant
Li-antioxidants ke likhomphutha tse thibelang kapa tse liehang ho senya lisele tse hlahisoang ke li-radicals tsa mahala. Li-radicals tsa mahala hangata li lebisa khatellong ea oxidative e amanang le ho baka ho ruruha le mafu a mang. Sesamol antioxidant e fumaneha ka oli ea sesame mme e bapala karolo ea bohlokoa ho sireng liseleng hore li se ke tsa senyeha ha oxidative.
Phuputsong ea likhoto tse 30 tsa banna tse bitsoang Wilstar albino, Isoproterenol (sehlopha sa ISO) e ile ea sebelisoa ho baka tšenyo e bakoang ke myocardial. Oli ea Sesame e fanoang ka molomo ho 5 le 10 ml / kg boima ba 'mele e bonts'a matla a sireletsang a Sesamol ka ho fokotsa ntho e sebetsang ea thiobarbituric acid (TBARS) le ho ntlafatsa ts'ebetso ea ho thibela antioxidant.
Antibacteria
Bacteria ke likokoana-hloko tse ka fumanoang kae kapa kae lefatšeng. Li ka ba molemo kapa tsa ba kotsi ho lebisang ho tsitsipaneng mafu a makhopho, tšoaetso ea pampiri ea urine hara mafu a mang. Sesamol e na le litlamorao tse khahlanong le baktheria tse e etsang hore e be karolo ea bohlokoa.
Boithuto bo bonts'itse ts'ebetso ea antimicrobial ea sesamol compound khahlano le likokoana-hloko tse 'maloa tsa baktheria le fungal.
Anti-inflammatory
Ho ruruha ke ts'ebetso e thusang 'mele ea ho itšireletsa khahlanong le lintho tse kantle ho ts'oaetso, likotsi le chefo tse thusang pholiso. Le ha ho le joalo, ho ruruha ho sa feleng ho etsahalang ha mmele o lula o le tlhokomelong ea nako e telele ho ka ba le phello e mpe 'meleng.
Tlatsetso ea Sesamol e tsejoa ho ba le thepa e ka khahlano le ho ruruha.
Phuputsong e entsoeng ka likhoto, tlatsetso ea Sesamol ho tlalehiloe ho fokotsa systemic lipopolysaccharide (LPS) -situsitse ho ruruha ha matšoafo ka thibelo ea karabelo ea ts'oaetso ea alveolar macrophage ho litoeba. Sesamol e lebisitse ho fokotseha ha likotsi tsa matšoafo le edema.
Phello ea Antitumor
Makhopho ke bongata ba lisele tse hlahisoang ke kholo ea lisele tse sa tloaelehang (lisele tse holang ebe 'mele ha o hloke' me o fapana le lisele tse tloaelehileng tse sa shoeng). Le ha e se lihlahala tsohle tse nang le mofetše, ho loketse ho li tlosa moo ho khonehang.
Bafuputsi ba 'maloa ba tlalehile hore Sesamol o na le litlamorao tse ling tse khahlanong le mofetše. Sesamol e bontšitsoe ho kenya apoptosis liseleng tse fapaneng tsa mofets'e.
Boithuto ba mahlale bo bontšitse hore Sesamol e lebisa ho kenngeng ha apoptosis liseleng tsa mofetše oa lefu la setho ka ho sitisa bokhoni ba membrane, ka hona, ho hloka taolo ea mitochondrial.
Khatello ea mali e tlaase
Khatello ea mali e phahameng ke boemo bo tloaelehileng bo ka bakang mathata a kang lefu la pelo (CVD), lefu la liphio le stroke.
Bopaki bo hlahisitsoeng kopanong ea selemo le selemo ea American Heart Association bo bontšitse hore Sesamol e na le bokhoni ba ho theola khatello ea mali. Phuputso e ne e kenyelletsa 133 basadi le 195 banna ka khatello ea mali. Kamora ho fuoa tlatsetso ea Sesamol ka matsatsi a mashome a tšeletseng, khatello ea mali ea bona e tlase e ile ea oela ka har'a maemo a tloaelehileng.
Sesamol (533-31-3) sebelisa khanya?
- E phahameng ho li-antioxidants
- E na le thepa e matla ea khahlanong le ts'oaetso
- E loketseng pelo ea hau
- E kanna ea thusa ho laola tsoekere ea mali
- E ka thusa ho phekola ramatiki
- Eka thusa ho folisa maqeba le ho chesoa
- Eka sireletsa khahlanong le mahlaseli a UV
- E ka ntlafatsa boleng ba boroko.
- Ho sebelisa lihlooho ho ka fokotsa bohloko.
- E ka ntlafala bophelo bo botle ba moriri.
Sesamol (533-31-3) kopo
Sesamol ke motsoako oa tlhaho oa tlhaho oo e leng karolo ea oli ea sesame. Sesamol e fumanoe e le antioxidant seo se ka thibela ho senyeha ha oli, 'me se ka sireletsa' mele ho senya ho tsoa ho li-radicals tsa mahala. E ka boela ea thibela ho senyeha ha oli ka ho sebetsa joalo ka antifungal. Oli ea Sesame e sebelisoa meriana ea Ayurvedic le sesamol may phetha karolo ea bohlokoa tšimong ena ea setso. Sesamol e na le lintho tse ngata tsa pharmacological tse kenyelletsang anti-inflammatory, antioxidant le neuroprotective properties. Sesamol pretreatment e fana ka tšireletso ea radio mme e thibela mahlaseli a bakoang ke chromosomal aberration ho li-lymphocyte tsa mali a motho.
Sesamol phofo Ho rekisoa(Moo u ka rekang phofo ea Sesamol ka bongata)
Khamphani ea rona e thabela likamano tsa nako e telele le bareki ba rona hobane re tsepamisitse maikutlo ho ts'ebeletso ea bareki le ho fana ka tse ntle dihlahiswa. Haeba u thahasella sehlahisoa sa rona, re tenyetseha le mokhoa oa ho etsa litaelo tse lumellanang le tlhoko ea hau e khethehileng le nako ea rona ea ho etella pele ka kotara ho tiisa hore u tla latsoa sehlahisoa sa rona ka nako. Re tsepamisa maikutlo hape ho lits'ebeletso tse eketsoang boleng. Re fumaneha bakeng sa lipotso tsa ts'ebeletso le tlhaiso-leseling ho ts'ehetsa khoebo ea hau.
Re barekisi ba phofo ea Sesamol ka lilemo tse 'maloa, rea fana lihlahisoa tse nang le tlholisano theko, 'me sehlahisoa sa rona ke sa boleng bo phahameng ka ho fetisisa 'me se etsoa liteko tse thata, tse ikemetseng ho netefatsa hore li bolokehile hore li ka sebelisoa lefatšeng ka bophara.
References
[1] Joo Yeon Kim, Dong Seong Choi le Mun Yhung Jung "Ketsahalo ea Antiphoto-oxidative ea Sesamol ho Methylene Blue- le Chlorophyll-Sensitized Photo-oxidation ea Oli" J. Agric. Lijo Chem., 51 (11), 3460 -3465, 2003.
[2] Wynn, James P .; Kendrick, Andrew; Ratledge, Colin. "Sesamol e thibela ho hola le metabolism ea lipid ho Mucor circinelloides ka ts'ebetso ea eona ea enzyme ea malic." Lipids (1997), 32 (6), 605-610.
[3] Ohsawa, Toshiko. "Sesamol le sesaminol e le li-antioxidants." Indasteri e ncha ea Lijo (1991), 33 (6), 1-5.
