Pyrroloquinoline Quinone disodium letsoai (122628-50-6)

April 9, 2020

Cofttek ke moetsi oa phofo e letsoai ea Pyrroloquinoline Quinone disodium e Chaena. Fektheri ea rona e na le sistimi e felletseng ea taolo ea tlhahiso (ISO9001 & ISO14001), e nang le tlhahiso ea khoeli le khoeli ea 2700kg.

 


Boemo: Ka Phatlalatso ea Mesebetsi
Sehlopha: 1kg / mokotla, 25kg / Drum

Pyrroloquinoline Quinone disodium letsoai (122628-50-6)

 

Pyrroloquinoline Quinone disodium letsoai Slitšobotsi

Name: Pyrroloquinoline Quinone disodium phofo ea letsoai
CAS: 122628-50-6
Ho hloeka 98%
Limolek'hule Mokgwa wa ho Nahana: C14H4N2Na2O8
Boima ba limolek'hule: 374.17 g / mol
Melt Point: N / A
Lebitso la k'hemik'hale Disodium 4,5-dihydro-4,5-dioxo-1H-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylate
Li-synonyms: Methoxatin Disodium

Methoxatin disodium letsoai

Methoxatin (letsoai la disodium)

Pyrroloquinoline quinone disodium letsoai

InChI Key: UFVBOGYDCJNLPM-UHFFFAOYSA-L
Halofo ea bophelo: N / A
Solubility: Soluble ho DMSO, Methanol, Metsi
Boemo ba ho Boloka: 0 - 4 C bakeng sa nako e khuts'oane (matsatsi ho isa ho libeke), kapa -20 C nako e telele (likhoeli)
e sebetsa joang: PQQ e sireletsa liseleng 'meleng ho tsoa ho li-oxidative senya mme e ts'ehetsa metabolism ea matla le botsofali bo phetseng hantle. E boetse e nkoa e le cofactor ea palesa e nang le ts'ebetso ea antioxidant le B ea mofuta oa B. E phahamisa bophelo bo botle ba kelello le memori ka ho loants'a ho se sebetse hantle ha methapo ea mali le ho sireletsa li-neuron ho tsoa tšenyo ea oxidative.
Ponahalo: phofo e sootho e khubelu

 

Pinroloquinoline Quinone (122628-50-6) Ponahalo ea NMR

Pyrroloquinoline Quinone (122628-50-6) - NMR Spectrum

Haeba o hloka COA, MSDS, HNMR bakeng sa sehlopha ka seng sa sehlahisoa le tlhaiso-leseling e ngoe, ka kopo ikopanye le rona mookameli oa papatso.

 

Pyrroloquinoline Quinone disodium letsoai ke eng (122628-50-6)?

Pyrroloquinoline Quinone disodium letsoai ke ntho e molomo, kahoo batho ba bangata ba rata ho sebelisa letsoai la PQQ disodium kapa PQQ. E boetse e bitsoa methoxatin. Joale PQQ disodium letsoai ke eng? PQQ disodium letsoai ke mofuta oa disodium oa PQQ, PQQ e ne e nahanoa hore ke mofuta oa vithamini, PQQ ka tlhaho e fumaneha lijong tsa meroho, litholoana le meroho e mengata (trace), mme lipalo tse phahameng tsa PQQ li ka fumanoa lihlahisoa tse tlotsitsoeng tsa soya, joalo ka kiwifruit, lychee, linaoa tse tala, tofu, rapeseed, mosetareta, tee e tala (camellia), pepere e tala, spinach, jj. Pyrroloquinoline quinone disodium letsoai (pqq), mofuta o motle ka ho fetisisa oa PQQ ke foromo ea phofo. empa batho ba bangata ba khetha ho e kenyelletsa lijong tsa bona ka li tlatselletso tsa PQQ.

 

Melemo ea Pyrroloquinoline Quinone disodium (122628-50-6) melemo

Melemo ea ho nka phofo ea letsoai la PQQ e ka kenyelletsa:

PUSELETSO E NTLE

Kaha mitochondria e hlahisa matla bakeng sa sele, 'me PQQ e thusa mitochondria ho sebetsa hantle, ho na le keketseho e akaretsang ea matla ka har'a lisele tsa hau. Matla a selefounu a sa sebelisoeng a fetisetsoa likarolong tse ling tsa 'mele oa hau. Haeba o loanela ho ba le matla a ho e qeta letsatsi lohle, kapa o ba le mokhathala kapa mokhathala, matla ana a eketsehileng a tsoang PPQ a tla ba bohlokoa ho uena. Phuputso e 'ngoe e fumane hore barupeluoa ba tlalehileng ba nang le mathata ka matla a bona, ba ile ba fokotseha ka mokhoa o hlokomelehang oa mokhathala oa bona kamora ho nka PQQ. Haeba u batla ho eketsa matla a hau, PQQ e kanna ea thusa ka seo.

BOKANG SLEEPE

Barupeluoa lithutong tse boletsoeng ka holimo ba boetse ba tlaleha hore ba khonne ho robala hantle ka mor'a ho nka PQQ bakeng sa libeke tse 8. Pele a qala thuto, bakuli bana ba ne ba bile le mathata a ho robala. PQQ e bonahala e fokotsa bongata ba cortisol, kapa lihormone tsa khatello ea maikutlo, ka har'a bakuli le ho ntlafatsa boroko ba bona. Le ha melemo ea PQQ ea ho robala e e-so ithutoe hantle, liphetho tsena tsa pele li bonahala li ts'episa.

PUSELETSO MOKOA

Ka khatello e fokolang ea maikutlo, bafuputsi ba se ba qalile ho bona ntlafatso ea mohopolo. Maemong ana, ho kopana ha PQQ le CoQ10 ho kanna ha lebisa ho ntlafatso ea mohopolo le ho holisa bophelo bo botle ba kelello. CoQ10, joalo ka PQQ, ke phepo e 'ngoe e ka fanang ka tšehetso ho mitochondria ea' mele. Hangata bakuli ba bangata ba talima PQQ le CoQ10 e le khetho kapa khetho, empa ho e nka le ho iphapanyetsa eona ho ka fella ka ho lahleheloa ke melemo e meng e meholo.

 

Pyrroloquinoline Quinone disodium letsoai (122628-50-6) Mokhoa oa ts'ebetso?

Pyrroloquinoline quinone (PQQ) ke molek'hule e nyane ea quinone, e nang le phello ea redox, e ka fokotsa oxidant (antioxidant); ebe e khutlisoa ka sebopeho se sebetsang ke glutathione. E bonahala e tsitsitse hobane e ka feta lits'ebetsong tse likete pele e tepella, 'me e ncha hobane e amana le sebopeho sa protheine ea lisele (li-antioxidants, li-carotenoids tse kholo tse kang beta-carotene le astaxanthin, li libakeng tse ikhethang tsa lisele, moo ba bapalang likarolo tsa antioxidant ka mokhoa o lekanang). Ka lebaka la ho ba haufi, PQQ e bonahala e bapala karolo haufi le liprotheine tse kang carotenoids ho membrane ea sele.

Mohlomong e hlokomelehang haholo ke phello ea PQQ ho mitochondria, e fanang ka matla (ATP) le ho laola metabolism ea sele. Bafuputsi ba hlokometse haholo phello ea PPQ ho mitochondria mme ba fumane hore PQQ e ka eketsa palo ea mitochondria esita le ho ntlafatsa ts'ebetso ea mitochondria. Lena ke lebaka la bohlokoa leo PPQ e leng bohlokoa hakana. Li-Enzymes tse nang le PQQ li tsejoa e le glucose dehydrogenase, protheine ea quinoa e sebelisoang e le sensor ea glucose.

 

Pyrroloquinoline Quinone disodium letsoai (122628-50-6) kopo

Pyrroloquinoline quinone (ho tloha joale PQQ) ke molek'hule e nyane ea quinone e nang le bokhoni ba ho ba moemeli oa REDOX, e khona ho fokotsa li-oxidants (phello ea antioxidant) ebe e nchafatsoa ke glutathione ho khutlela mofuteng o sebetsang. E bonahala e tsitsitse haholo kaha e khona ho tsamaea ka potoloho ea likete tse 'maloa pele e ka sebelisoa,' me e sa tsoa ngola kaha e amana le likarolo tsa protheine ka seleng (li-antioxidants, haholo li-carotenoids tse kang β-carotene le astaxanthin, li libakeng tse ikhethang. sa sele eo ho eona li nang le litlamorao tse eketsehileng tsa antioxidant ka lebaka la ho ba haufi; PQQ e bonahala e etsa liprotheine tse kang carotenoids li etsa joalo ka membrane ea sele).

 

Pyrroloquinoline Quinone disodium letsoai phofo Ho rekisoa(U ka reka Pyrroloquinoline Quinone disodium phofo ka bongata ka bongata)

Khamphani ea rona e thabela likamano tsa nako e telele le bareki ba rona hobane re tsepamisa maikutlo mosebetsing oa bareki le ho fana ka lihlahisoa tse ntle. Haeba o rata sehlahisoa sa rona, re feto-fetoha le maemo ka mokhoa oo re ratang ho odara ka oona o lekanang tlhoko ea hau le nako ea hau ea kapele ea li-odara e tiisa hore o tla latsoa sehlahisoa sa rona ka nako. Re shebile hape le lits'ebeletso tse kenyellelitsoeng boleng. Re fumaneha bakeng sa lipotso tsa ts'ebeletso le tlhaiso-leseling ho ts'ehetsa khoebo ea hau.

Re le mofani oa Pyrroloquinoline Quinone disodium letsoai la phofo ea letsoai ka lilemo tse 'maloa, re fana ka lihlahisoa ka theko ea tlholisano,' me sehlahisoa sa rona ke sa boleng bo holimo ebile sea hlahlojoa ka thata, se ikemetseng ho netefatsa hore se bolokehile bakeng sa ts'ebeliso lefatšeng ka bophara.

 

References

  1. Ameyama M, Matsushita K, Ohno Y, Shinagawa E, Adachi O (1981). "Ho ba teng hoa sehlopha sa maiketsetso sa maiketsetso, PQQ, ka sehokelo sa khokahano e tsamaeang ka methapo, sehokelo sa elektrone," dehydrogenase ea mantlha ea libaktheria tse nang le oxidative ". FEBS Lett. 130 (2): 179-83. Doi: 10.1016 / 0014-5793 (81) 81114-3. PMID 6793395.
  2. Haft DH (2011). "Bopaki ba Bioinformatic bakeng sa moqapi oa sephethephethe oa elektronike o phatlalalitsoeng ka bongata, liprotheine tsa eona tsa mmele tse matlafatsang le balekane ba eona" BMC Genomics. 12: 21. Doi: 10.1186 / 1471-2164-12-21. PMC 3023750. PMID 21223593.
  3. Ameyama M, Matsushita K, Shinagawa E, Hayashi M, Adachi O (1988). "Pyrroloquinoline quinone: excretion ka methylotrophs le tlhoko ea kholo bakeng sa likokoana-hloko". Li-BioFactors. 1 (1): 51–3. PMID 2855583.