Kamora phuputso ea 2019 e phethetse seo Nicotinamide Mononucleotide e bolokehile bakeng sa ts'ebeliso ea batho haeba ts'ebeliso ea eona e thibetsoe moeli o behiloeng, lik'hamphani tse 'maloa tsa tlhahiso li kene' marakeng ka linyehelo tsa tsona. Ts'ebetso ena e ngata haholo ea likhetho e siile bareki ba ferekane ka hore na Tlatsetso ea Nictonimade Mononucleotide (NMN) e molemohali bakeng sa bona. Ka maikutlo a rona, tlatsetso e khahlano le botsofali ea Nicotinamide Mononucleotide (NMN) ho 2021 ke k'hamphani ea Cofttek.
Cofttek ke k'hamphani e lekantsoeng ea A + e bileng 'marakeng ka lilemo tse ka bang 12 mme e thehile setsi sa balateli ba tšepahalang nakong ena. Phofo ea NMN e fanoang ke k'hamphani e lekoa habeli ka laborateng, ke NMN ea boemo ba meriana e tsoang likhamphaning tse tšoanang tse neng li fane ka NMN bakeng sa liteko tse fapaneng tsa bongaka tsa batho tse etsahetseng ho theosa le lilemo. The Phofo ea NMN e fanoa ke Cofttek e nolofalletsa ho kenngoa habonolo ha eona 'meleng, ka tsela eo e eketsa ts'ebetso ea bioavailability ea sehlahisoa hammoho le mesebetsi ea eona ea' mele. Habohlokoa le ho feta, phofo ena e tla ka bongata mme u ka e boloka ka likhoeli tse tharo. Ka kakaretso, ena ke e 'ngoe ea li tlatselletso tse fumanehang' marakeng ka tekanyo e phahameng ea basebelisi 'me e tsoa ho khamphani e tsamaisitseng lihlahisoa tse tšepahalang le tse sebetsang selemo le selemo.

LBH

Nicotinamide Mononucleotide (NMN) ke eng?

Nicotinamide Mononucleotide (1094-61-7kapa NMN ke nucleotide e teng ka tlhaho lijong tse ngata tseo re li jang. E fumanoa ka avocado, broccoli, likomkomere, k'habeche, edamame le tamati. Leha ho le joalo, bongata ba NMN bo fanoang ke lijo tsena ha boa lekana ho ts'ehetsa mesebetsi ea mantlha ea 'mele ka hona, hangata batho ba eletsoa ho nka litlatsetso tsa NMN. Empa, hobaneng ha NMN e le bohlokoa haholo bakeng sa 'mele?

Nicotinamide Mononucleotide kapa NMN ke selelekela sa Nicotinamide Adenine Dinucleotide kapa NAD +. Ka mantsoe a bonolo, NMN ke kompone e fetohang NAD + ka letoto la liphetoho tsa lik'hemik'hale tse etsahalang ka har'a lisele. Ka lehlakoreng le leng, NAD + e nkuoa e le bohlokoa bakeng sa 'mele kaha e etsa mesebetsi e' maloa ea bohlokoa, ho kenyelletsa ho leka-lekanya morethetho oa 'mele oa circadian, ho heletsa limatlafatsi ho lokolla matla a cellular, le ho thusa liphetoho tsa bohlokoa tsa enzymatic, tse ling tsa tsona li liehisa botsofali. Ka bomalimabe, leha NAD + e fumaneha kahare ho sele e ngoe le e ngoe ea 'mele, tlhahiso ea eona ea fokotseha ka lilemo. Habohlokoa le ho feta, ha ho na lijo tseo motho a ka li jang ho eketsa tlhahiso ea NAD + ka har'a 'mele. Ke ka hona, 'mele o hlokang selelekela sa NAD + se fetohang NAD + ka har'a sele, ka tsela eo se lekanyetse ho theoha ha sona kahare ho mmele. Mona ke moo ts'ebeliso ea litlatsetso tsa NMN e kenang.

Nmn e ntle bakeng sa eng?

NMN e fumanoe e ntlafatsa tšebetso ea insulin le tlhahiso, e hlahisang melemo e meng ea ts'oaetso le mamello ea tsoekere. Haholo-holo li-supplements tsa NMN li ka thusa ho sebetsa ho fokotsa maemo a ts'oaetso a kang lefu la tsoekere, lefu la mafura a sebete le botenya.

Na Nmn e ka khutlisa botsofali?

Tsamaiso ea nicotinamide mononucleotide (NMN) Tlhatlhobo ea Nicotinamide mononucleotide (NMN) e khothaletsa profil ea polelo ea anti-botsofe ea miRNA ho aorta ea litoeba tse tsofetseng, ho bolela esale pele ntlafatso ea epigenetic le litlamorao tsa anti-atherogenic.

U eketsa Nmn joang ka tlhaho?

NMN e ka fuoa litoeba ka polokeho 'me e fumanoa ka tlhaho lijong tse' maloa, ho kenyeletsoa broccoli, k'habeche, likomkomere, edamame le avocado. Phuputso e ncha e bonts'a hore ha NMN e qhibiliha ka metsing a nooang ebe e fuoa litoeba, e hlaha maling ka nako e ka tlase ho metsotso e meraro.

Na Nmn e ka eketsa nako e telele?

Bo-rasaense ba ithutile lipakeng tse peli tse joalo, nicotinamide riboside (NR) le nicotinamide mononucleotide (NMN), haholo ho feta tse ling, mme lipatlisiso li a khothatsa. Liphuputso tse 'maloa li bonts'a hore ho tlatselletsa ka li-precursors tsena ho ka eketsa maemo a NAD + le ho lelefatsa nako ea bophelo ea tomoso, liboko le litoeba.

Nmn e lula nako e kae tsamaisong ea hau?

Boithuto ba rona ba hajoale bo bontša ka ho hlaka hore NMN e kenella kapele ho tsoa ka maleng ho potoloha mali kahare ho metsotso e 2-3 mme hape e hlakoloe ho tloha phallong ea mali ho ea ho lisele tse ka hare ho 15 min.

Ho etsahalang ha o emisa ho nka Nmn?

Resveratol le NMN li sebetsa ka ho ntlafatsa bokhoni ba lisele tsa 'mele oa hau ho itokisa. Kahoo, haeba u li nka nakoana ebe u li emisa ho ke ke ha u etsa hore u khutlele setulong seo u neng u le ho sona hanghang hobane liphetoho ke ntlafatso ea 'nete ea ts'ebetso ea sele.

Na Nmn e etsa hore u shebahale u le monyane?

Laboratori ea rona e bonts'itse hore ho fa litoeba NMN likhoeli tse fetang 12 ho bonts'a litlamorao tse khahlano le botsofali. " Ho ea ka Imai, ho fetolela liphetho ho batho ho supa hore NMN e ka fa motho metabolism e nyane ea lilemo tse 10 ho isa ho tse 20.

Ke eng tlatsetso e ntlehali bakeng sa letlalo le tsofetseng?

Lisebelisoa tse 12 tsa ho loantša botsofali

  • Curcumin
  • EGCG
  • Collagen
  • CoQ10
  • Nicotinamide riboside le nicotinamide mononucleotide
  • Crocin
  • Theanine
  • Rhodiola
  • Konofolo
  • Astragalus
  • Fisetin
  • Resveratrol

Nka etsolla wrinkles ka tlhaho?

  • Roala mahlaseli a letsatsi.
  • Fokotsa ho ja tsoekere.
  • Khaotsa ho tsuba.
  • Sebelisa oli ea coconut.
  • Nka beta carotene.
  • Noa tee ea lekhasi la sirilamunu.
  • Fetola boemo ba boroko.
  • Hlatsoa sefahleho.
  • Qoba khanya ea mahlaseli a kotsi
  • Hlahisa li-antioxidants tsa hau

Nka fetola letlalo le tsofetseng joang?

Ho thusa bakuli ba bona ho thibela botsofali ba letlalo pele ho nako, lingaka tsa letlalo li fa bakuli ba tsona likeletso tse latelang.

  • Sireletsa letlalo la hao letsatsing letsatsi le leng le le leng.
  • Sebelisa letlalo la boithati ho e-na le ho le etsa.
  • Haeba u tsuba, emisa.
  • Qoba ponahalo ea sefahleho e pheta-phetoang.
  • Ja lijo tse phetseng hantle, tse leka-lekaneng.
  • Noa joala bo fokolang.
  • Ikoetlise matsatsi a mangata bekeng.
  • Hlatsoa letlalo ka bonolo.
  • Hlatsoa sefahleho habeli ka letsatsi le kamora ho fufuleloa haholo.
  • Khaotsa ho sebelisa lihlahisoa tsa tlhokomelo ea letlalo tse hlabang kapa tse tukang.

Sinclair o khothaletsa eng?

David Sinclair o nka:

Resveratrol - 1g / letsatsi le leng le le leng - hoseng ka yogurt (bona moo o ka rekang) Nicotinamide Mononucleotide (NMN) - 1g / letsatsi le letsatsi - hoseng (bona moo o ka rekang) Metformin (setlhare se tlamang) - 1g / letsatsi le letsatsi - 0.5g hoseng le 0.5g bosiu - ntle le ha motho a ikoetlisa.

Na Nmn e na le litla-morao?

Ha e nooa ka molomo: Nicotinamide riboside e KA SIRELETSA HAE sebelisoa ha nako e khuts'oane. Litla-morao tsa nicotinamide riboside hangata li bobebe. Litla-morao li ka kenyelletsa mathata a mala a kang ho nyekeloa ke pelo le ho ruruha kapa mathata a letlalo joalo ka ho hlohlona le ho fufuleloa haholo.

Litla-morao tsa Resveratrol ke life?

Ha e nooa ka molomo: Resveratrol E KA SIRELETSEHA HA E sebelisoa ka bongata bo fumanoang lijong. Ha e nooa ka tekanyetso ho fihlela ho 1500 mg letsatsi le letsatsi ho fihlela likhoeli tse 3, resveratrol ke POSSIBLY SAFE. Litekanyo tse phahameng ho fihlela 2000-3000 mg letsatsi le letsatsi li sebelisitsoe ka mokhoa o sireletsehileng bakeng sa likhoeli tse 2-6. Leha ho le joalo, litekanyetso tsena tse phahameng tsa resveratrol li na le monyetla oa ho baka mathata a mala.

Na nicotinamide e bolokehile ho e nka letsatsi le letsatsi?

Nicotinamide riboside e sireletsehile ha ho na le litla-morao tse fokolang - haeba li le teng. Lithutong tsa batho, ho nka 1,000-2,000 mg ka letsatsi ho ne ho se na litlamorao tse mpe. Leha ho le joalo, lithuto tsa batho tse ngata li khuts'oane ka nako ebile li na le barupeluoa ba fokolang haholo. Bakeng sa mohopolo o nepahetseng haholoanyane oa polokeho ea eona, ho hlokahala lithuto tsa batho tse matlafatsang.

Hobaneng ha NADH e le ngata haholo?

NADH ena e feteletseng e ka senya tekano ea redox lipakeng tsa NADH le NAD +, mme qetellong e ka lebisa ho khatello ea mali le mefuta e fapaneng ea syndromes ea metabolic.

Ke efe e ntle ea Nmn kapa NR?

NR hangata ho nahanoa hore ke selelekela se sebetsang hantle haholo ho NAD +, empa molek'hule ea motsoala oa eona NMN, leha e se sesebelisoa Basis, e phahamisa lintši joalo ka ngoana e mocha.

NMN e kholo feela ho feta NR, ho bolelang hore hangata e hloka ho rojoa hore e lekane ka seleng. NR, ha e bapisoa le tse ling tsa pele ho NAD + (joalo ka nicotinic acid kapa nicotinamide) e busa ka mokhoa o phahameng ka ho fetisisa. Empa fa NMN monyako o mocha, o ka kenang ho oona, 'me ke papali e ncha.

Tlatsetso e ntle ea Nmn ke efe?

  • Ke Nmn supplement efe e ntle ka ho fetisisa?
  • Matlapa a Sublingual a NMN.
  • NAD + Liposomal ea Khauta NMN.
  • Li-capsules tsa NMN.

Na Nmn e khutlisetsa botsofali?

Litsela tsa ho qobella keketseho ea maemo a NAD + li bonts'itsoe ho ntlafatsa ts'ebetso ea mitochondrial liphoofolong tsa khale, ho khutlisa tse ling tsa tahlehelo e bang teng ka lilemo. Tsamaiso ea nicotinamide mononucleotide (NMN) e bonts'itsoe ho fokotsa mathata a amanang le botsofali.

U lokela ho nka NMN e kae?

Le ha liphuputso li netefalitse hore Nicotinamide Mononucleotide kapa NMN e bolokehile bakeng sa ts'ebeliso ea batho, lipatlisiso li ntse li etsoa ho fumana litekanyo le makhetlo a sebetsang ka ho fetesisa a tekanyetso ea NMN bathong. Leha ho le joalo, lithuto tse entsoeng ho fihlela joale li netefalitse hore litekanyetso tsa 500 mg ka letsatsi li bolokehile bakeng sa banna. Matsatsing ana, Nicotinamide Mononucleotide e fumaneha ka mefuta e fapaneng, ho kenyeletsoa lipilisi le phofo. Barekisi ba tlatsetso ea NMN ba re litlatsetso tsa molomo li sebetsa hantle ho matlafatseng tlhahiso ea NAD + 'meleng. Lipolelo tsena li ipapisitse le taba ea hore Slc12a8, mothiri oa nicotinamide nucleotide, o thusa ka ho monya NMN ka maleng.

Na Nmn e ts'oana le b3?

NMN ha e joalo. NMN ha se mofuta oa vithamine B3, mme ha ho na liteko tsa bongaka ho paka hore e eketsa NAD bathong. NMN hape ha se mofuta oa molek'hule e ka nkoang e le vithamine kaha e na le phosphate, e amang bokhoni ba eona ba ho kena liseleng.

Ke lijo life tse nang le NAD + e phahameng ka ho fetisisa?

Lijo tse matlafatsang maemo a NAD

Ho na le lijo tse ling tse ka matlafatsang maemo a NAD 'meleng. Tse ling tsa tsona li kenyelletsa:

  • Lebese la lebese - patlisiso e bontšitse hore lebese la khomo ke mohloli o motle oa Riboside Nicotinamide (RN). Litara ea lebese la khomo e sa tsoa khuoa e na le hoo e ka bang 3.9 XNUMX.mol ea NAD +. Kahoo ha u ntse u natefeloa ke khalase e khathollang ea lebese, u ntse u hola le ho phela hantle 'meleng!
  • Litlhapi - mona ke lebaka le leng la hore u natefeloe ke litlhapi! mefuta e meng ea litlhapi tse kang tuna, salmon le sardine ke mehloli e metle ea NAD + bakeng sa 'mele.
  • Li-mushroom - batho ba bangata ba rata li-mushroom le bona e le sejo se tloaelehileng lijong tsa bona tse tloaelehileng. Empa na u ne u tseba hore li-mushroom, haholo li-mushroom tsa crimini, le tsona li thusa ho matlafatsa maemo a NAD ka tlhaho. E, ke 'nete. Kahoo, natefeloa ke ho ja li-mushroom 'me u tsoele pele ho shebahala le ho ba monyane hape u le mocha haholoanyane!
  • Tomoso - tomoso ke sesebelisoa se sebelisetsoang ho etsa bohobe le lihlahisoa tse ling tsa bohobe. Tomoso e na le Riboside Nicotinamide (RN), e leng selelekela sa NAD. Mona ke lebaka le leng la hore o natefeloe ke libeche kapa libanse tseo u li ratang nako le nako ha o etela bakery! Natefeloa ke lijo tseo u li ratang ha o ntse o matlafatsa maemo a NAD ka nako e le 'ngoe. Ho pholile hakaakang!
  • Meroho e Tala - meroho e metala e na le mefuta eohle ea limatlafatsi tse ho eona e leng molemo ka litsela tse fapaneng. Haufinyane, ho hlahile hore meroho e metala hape ke mohloli o motle oa NAD bakeng sa 'mele. E meng ea meroho ena e kenyelletsa lierekisi le asparagase.
  • Lithollo Tsohle - joalo ka ha ho boletsoe pejana, Vithamine B3 e boetse e na le RN, selelekela sa NAD. Leha ho le joalo, ha meroho, lijo kapa lijo-thollo li phehiloe kapa li sebetsoa, ​​li lahleheloa ke phepo e nepahetseng hammoho le mohloli oa vithamine. Ka hona, ho kgothaletswa hore o lokela hape ho ja meroho e tala mme o nke lijo-thollo tse felletseng ho fapana le lijo tse sebelisitsoeng.
  • Fokotsa lino tse tahang - NAD e ikarabella ho boloka lits'ebetso tsa 'mele tsa' mele. Joala bo tloaetse ho kena-kenana le lits'ebetso tsena le ho fokotsa ts'ebetso ea NAD. Ka hona, o lokela ho qoba ho noa lino tse tahang haholo hobane le tsona ha li na thuso molemong oa bophelo bo botle.

Na Nmn e baka ho hohola?

'Niacin flush' ke litla-morao tsa ho noa litekanyetso tse phahameng tsa niacin ea tlatsetso (Vitamin B3). Ho phatloha ho etsahala ha niacin e etsa hore li-capillaries tse nyane letlalong la hao li phahame, e leng ho eketsang phallo ea mali holima letlalo. Ho fapana le livithamini tsa B3 (niacin) tse tlatsetsang, nicotinamide riboside ha ea lokela ho baka ho fofa sefahlehong.

Nka reka Nmn kae Canada?

NMN ke nucleotide e tsoang ho ribose le nicotinamide. Joalo ka nicotinamide riboside (Niagen), NMN e tsoa ho niacin, le selelekela sa NAD +. NMN Canada: Nicotinamide mononucleotide ha e fumanehe hajoale e le tlatsetso ea lijo Canada.

Na Nmn e bolokehile?

Ho theosa le lilemo, ho entsoe lithuto tse 'maloa ho ithuta hore na ts'ebeliso ea NMN bathong e bolokehile kapa che. Lithuto tsena li bontšitse khafetsa hore ts'ebeliso ea Nicotinamide Mononucleotide e bolokehile ka botlalo ha litekanyetso tsa eona li thibetsoe. Ka kakaretso, banna ba eletsoa ho khomarela tekanyetso ea letsatsi le letsatsi e ka tlase ho 500 mg. Leha ho le joalo, ho tlameha ho totobatsoa hore FDA ha e so ananele NMN joalo ka sethethefatsi se bolokehileng. Kahoo, haeba o na le ho kula kapa mathata a bongaka, ho molemo hore o botse ngaka ea hau pele o qala litlatsetso tsa NMN.

Ke efe e molemo NAD kapa NMN?

NAD le NMN ke metsoako e tsebahalang ea ho tlatsetsa botsofaling, 'me ka mabaka a utloahalang.

Nka eketsa NAD + ka tlhaho joang?

Methati ea Bohlokoa ea NAD

  • Ho itima lijo
  • Lisebelisoa tsa phepelo ea lijo tsa Nicotinamide Riboside
  • ho ikoetlisa
  • Khanya ea Letsatsi e ngata haholo e kanna ea se be ntle!
  • Lijo tse matlafatsang maemo a NAD

Ke lokela ho tlisa eng ka NMN?

Ho ntlafatsa maemo a hau a NAD, o ka nka li-capsule tsa NMN tse lokolotsoeng ka Sirtuin Activator joalo ka Resveratrol e nang le yogurt e mafura a felletseng e thusang ho fumaneha ha Resveratrol.

Na ke lokela ho nka TMG le NMN?

Haeba ha joale u ntse u nka NMN kapa u nahana ho qala, nahana ka ho e kopanya le TMG e le ts'ehetso e ekelitsoeng ea methylation. Bafani ba bang ba methyl ba ka bang molemo ba kenyelletsa methylated B6, B12 le folate.

Phapang ke efe lipakeng tsa nicotinamide le nicotinamide riboside? (3)

Niacin ke mofuta o mong oa nicotine oo 'mele o ka o fetolang ho NAD. Nicotinamide ke amide ea niacin e ts'oanang le NAD ebile e na le litla-morao tse fokolang. Nicotinamide riboside ke mofuta oa maiketsetso oa nicotinamide o nang le litšobotsi tse fapaneng.

Na Nmn ke niacin?

Joalo ka nicotinamide riboside, NMN ke sehlahisoa sa niacin, mme batho ba na le li-enzyme tse ka sebelisang NMN ho hlahisa nicotinamide adenine dinucleotide (NADH). Ka litoeba, NMN e kenella liseleng ka mala a manyane nakong ea metsotso e 10 e fetohela NAD + ka sepalangoang sa Slc12a8 NMN.

Na nicotinamide riboside e theola BP?

Nicotinamide riboside ke selelekela sa nicotinamide adenine dinucleotide (NAD +), mokena-lipakeng ea mahlonoko oa litlamorao tsa thibelo ea `` caloric '', ka hona ke "novel" caloric thibelo ea mimetic komponeng. Re sa tsoa phethela thuto ea pele ea mofofisi oa nicotinamide riboside supplementation ho batho ba baholo ba lilemong tse bohareng le ba baholo mme re bonts'itse hore libeke tse 6 tsa tlatsetso li fokotse khatello ea mali ea systolic (SBP) ka 8 mmHg ho batho ba nang le SBP ea mantlha ea 120-139 mmHg (SBP e phahameng) Stage 1 hypertension) ha e bapisoa le placebo, le ho theola ho tiea ha methapo, motho ea ikemetseng ea ikemetseng oa CVD le mafu a amanang le lefu.

Betaine e fumanoa kae?

Betaine e fumanoa ho likokoana-hloko, limela le liphoofolo 'me ke karolo ea bohlokoa lijong tse ngata, ho kenyeletsoa koro, khofu, spinach le li-beet tse tsoekere. Betaine ke motsoako oa zwitterionic quaternary ammonium o tsejoang hape e le trimethylglycine, glycine betaine, lycine le oxyneurine.

Ke lijo life tse emisang makhopo?

Mona ke tse 10 tsa lijo tse loantšang botsofali ho fepa 'mele oa hau bakeng sa khanya e tsoang kahare.

  • Motlolo oa metsi
  • Pepere e khubelu ea tšepe
  • Papaya
  • Blueberries
  • Broccoli
  • Sepinichi
  • Nuts
  •  
  • Litapole tse monate
  • Peo ea kharenate

Nka shebahala ke le monyane lilemong tse 10 joang?

  • Sebelisa Mask ea Hydrating.
  • Khetha Motheo o khanyang
  • Fokotsa Moriri oa Hao Hanyane
  • Apara Ponytail
  • Exfoliate (Empa U se ke Ua e Fetella)
  • Tšoeu Metsi a Hau
  • Qetella Ponahalo ea Hau ka Sekoli sa Minerale

Nka thibela sefahleho sa ka ho tsofala joang?

  • Sireletsa letlalo la hao letsatsing letsatsi le leng le le leng
  • Sebelisa letlalo la boithati ho e-na le ho le etsa
  • Haeba u tsuba, emisa
  • Qoba ponahalo ea sefahleho e pheta-phetoang
  • Ja lijo tse phetseng hantle, tse leka-lekaneng
  • Noa joala bo fokolang
  • Ikoetlise matsatsi a mangata bekeng
  • Hlatsoa letlalo ka bonolo

Ke lijo life tse etsang hore u tsofale kapele?

  1. Litapole tse monate tsa litapole bakeng sa mafora a French
  2. Bohobe bo mosoeu ba bohobe bo bosoeu
  3. Mahe a linotši kapa litholoana tsa tsoekere e tšoeu
  4. Oli ea mohloaare kapa li-avocado bakeng sa majarine
  5. Khomarela likhoho bakeng sa nama e sebetsitsoeng
  6. Utloa ka lebese
  7. Nahana habeli ka soda le kofi
  8. Noa joala ka teka-tekano
  9. Qoba ho pheha ka mocheso o phahameng
  10. Tlosa mahobe a raese
  11. Counteract fructose le lipoic acid

Ke vithamine efe e loketseng makhopo a sefahleho?

Vithamine C e ka thusa ho loants'a matšoao a botsofali ka lebaka la karolo ea eona ea bohlokoa 'meleng oa tlhaho oa collagen. E thusa ho folisa letlalo le senyehileng mme, maemong a mang, e fokotsa ponahalo ea makhopo. Ho noa vithamine C e lekaneng ho ka thusa ho lokisa le ho thibela letlalo le omeletseng.

Hobaneng ha re hloka Nicotinamide Mononucleotide (NMN)?

Botsofali bo amana le nako ebile bo thusa nako ho khutlisa tšebetso ea 'mele ea motho. Leha botsofe bo ke keng ba qojoa ebile bo ke ke ba qojoa, boramahlale ba sebelisitse lilemo ho utloisisa hore na ts'ebetso ena e ka lieha le ho laoloa joang. Patlisiso ena e tsoelang pele e lebisitse ho sibolloeng ha lintho tse 'maloa le metsoako e nang le thepa e loantšang botsofali e ka fetoloang e le lisebelisoa tse khahlano le botsofali. E 'ngoe ea likarolo tse joalo tse nang le thepa ea bohlokoa e khahlanong le botsofali eo bo-rasaense ba utloang ba khahliloe ke NMN kapa Nicotinamide Mononucleotide. Sehloohong sena, re tšohla ntho e ngoe le e ngoe eo re lokelang ho e tseba ka NMN hammoho le tlatsetso e ntle ka ho fetesisa ea botsofali ea nicotinamide mononucleotide ho 2021.

Ts'ebeliso ea Nicotinamide Mononucleotide (NMN)

Ho fihlela lilemong tse 'maloa tse fetileng, lithuto tsohle tse amanang le ts'ebeliso ea NMN li ne li etsoa liphoofolong mme ha lithuto tsena li bonts'a sephetho se ts'episang, liphetho tsena li ne li sa lekana ho hlahisa melemo ea ts'ebeliso ea NMN bathong. Ka 2016, ho ile ha etsoa phuputso ho sekaseka polokeho ea ts'ebeliso ea NMN le nako ea eona maling a batho. Phuputso e hlahisitse liphetho tse tšepisang. Romella hore, phuputso e 'ngoe e entsoe ka 2016 ho ithuta phello ea ts'ebeliso ea NMN ho basali ba baholo ba 50 ba nang le BMI e phahameng, tsoekere ea mali le triglycerides ea mali. Thuto e ile ea atleha. Leha ho le joalo, kaha lebala la boithuto le ne le lekanyelitsoe basali ba lilemo tse itseng feela, boramahlale ba ne ba lumela hore ho hlokahala bopaki bo bongata ho netefatsa hore ts'ebeliso ea NMN e bolokehile bakeng sa batho.

Ka hona, haufinyane tjena, ho 2019, ho ile ha etsoa thuto Lefapheng la Teko ea Kliniki ea Keio University School of Medicine. Sehlooho sa thuto e ne e le banna ba 10 ba lilemo li pakeng tsa 40 le 60. Banna bana ba ne ba fuoa litekanyo tse tsoang ho 100 mg ho isa 500 mg. Phuputso e phethetse hore NMN e mamelloa hantle ke batho mme e bolokehile ho e ja ha feela ts'ebeliso ea eona e laoloa hantle. Boithuto bona bo ne bo le bohlokoa joalo ka ha e bile thuto ea pele ea NMN e ileng ea etsoa ho batho ho ithuta phello ea NMN ho bophelo bo botle ba batho ka kakaretso. Hang ha ho netefatsoa hore ts'ebeliso ea NMN e bolokehile, bahlahisi ba ile ba qala ho hlasela 'maraka ka li-supplement tsa NMN, tse seng li atile haholo matsatsing ana. (2) Yoshino, J., et al. (2011)….

melemo e

Karolong ena, re tšohla melemo e ka bang teng e amanang le melemo ea Nicotinamide Mononucleotide kapa ea NMN.

N NMN e Thibela ho Tsofala

O mong oa melemo e meholo ea NMN ke hore o fokotsa ts'ebetso ea botsofaling. Lilemong tse 'maloa tse fetileng David Sinclair, setsebi se tsebahalang sa Biology ea Australia le profesa ea Genetics, o fane ka bopaki ba hore NAD + e liehisa ho tsofala le ho qala ha mafu a amanang le lilemo ho batho. Leha ho le joalo, tlhahiso ea NAD + e fokotseha ka lilemo. Kahoo, ha batho ba ntse ba tsofala, tlhoko ea moetapele oa NAD + ea eketseha ka har'a 'mele ea bona. Mona ke moo NMN e kenang teng: NMN e kena ka liseleng ebe e ba le liphetoho tse ngata tsa lik'hemik'hale pele e fetoha NAD + 'me e fokotsa lits'ebetso tsa botsofaling.

② Batho ba nang le lefu la tsoekere ba ka una molemo ka ts'ebeliso ea lona

Ho ile ha etsoa boithuto ba ho ithuta hore na tlatsetso ea molomo ea NMN e thusitse joang ka ho ja le lefu la tsoekere le amanang le lilemo ho litoeba. Phuputso e senotse hore litoeba tse fanoeng tlatsetso ea NMN ea molomo li bonts'a kutloisiso e eketsehileng ea insulin hammoho le secretion ea eona e eketsehang. Phuputso ena e fane ka leseli la hore Nikotinamide Mononucleotide kapa tlatsetso ea molomo ea NMN e ka thusa batho ba nang le lefu la tsoekere.

Tšebeliso ea NMN e boetse e hokahane le bophelo bo ntlafetseng ba pelo

Phuputso e 'ngoe e entsoe ho ithuta hore na tlatsetso ea NMN e amme bophelo ba pelo joang ho lithutong Boithuto bo senotse hore NMN ha e khutlisetse ts'ebetso ea mali e amanang le lilemo le tšenyo ea capillary ho litoeba empa e boetse e lebisitse ho phallang phallo ea mali. Se ileng sa makatsa haholo ke taba ea hore litoneng tse fuoeng tlatsetso ea molomo ea NMN, ho phatloha ha methapo e mecha ea mali ho bonoe. Haufinyane tjena, ho entsoe thuto e 'ngoe ho ithuta ka sephetho sa NMN ho bophelo bo botle ba litoeba mme boithuto bona le bona bo hlahisa litholoana tse tšoanang. Lithuto tsena li fane ka bopaki bo lekaneng ho bafuputsi ho lumela hore tšebeliso ea NMN e boetse e nts'etsapele bophelo bo botle ba pelo ho batho.

Nicotinamide Mononucleotide (NMN)

④ Batho ba nang le Alzheimer's ba ka una molemo ho ts'ebeliso ea NMN

Ho batho ba nang le lefu la Alzheimer, maemo a NAD a theoha haholo. Kahoo, ha batho ba nang le lefu la Alzheimer ba sebelisa NMN, 'mele o arabela ka ho eketsa palo ea NAD +, eo le eona e lebisang ho eketsa taolo ea makoloi, ho eketsa ts'ebetso ea liphatsa tsa lefutso tsa SIRT3, ho ntlafatsa mohopolo le ho fokotsa ts'oaetso ea methapo. Kahoo, batho ba nang le lefu la Alzheimer ba ka una molemo ka ho ja NMN.

⑤ NMN e Ntlafatsa Mosebetsi oa Liphio

Tlatsetso ea molomo ea NMN e amahanngoa le ts'ebetso e ntlafalitsoeng ea menoana. Sena ke hobane NMN e eketsa tlhahiso ea NAD + le SIRT1, tseo ka bobeli li hokahantsoeng le tšebetso e ntlafatsang ea meno.

Moo u ka rekang phofo ea Nicotinamide Mononucleotide (NMN) ka bongata?

Haeba u batla ho reka phofo ea Nicotinamide Mononucleotide (NMN) ka bongata, sebaka se setle sa ho reka phofo ea NMN ke cofttek.com. Cofttek ke khoebo ea theknoloji e phahameng e 'nileng ea fana ka lihlahisoa tse ncha le tsa boleng bo holimo ho tloha ka 2008. Khamphani e ithorisa ka sehlopha se tsotehang sa R&D se nang le boiphihlelo bo ikemiselitseng ho hlahisa lihlahisoa tsa tlholisano. Cofttek e na le balekane 'me e fana ka lihlahisoa tsa eona lik'hamphaning tsa meriana Chaena, Europe, India le Amerika Leboea. Β-Nicotinamide Mononucleotide e fanoang ke Cofttek ke ea boleng bo holimo haholo 'me e bolokehile ka ho felletseng hore e ka sebelisoa ke batho. Habohlokoa le ho feta, k'hamphani e fana ka phofo ena ka bongata, ke hore, ka li-unit tsa 25kgs. Kahoo, haeba u batla ho reka phofo ena ka bongata, Cofttek ke k'hamphani eo u lokelang ho ikopanya le eona - ke bona ba fanang ka phofo ea Nicotinamide Mononucleotide (NMN) 'marakeng.

Lenaneo la Nicotinamide Mononucleotide (NMN)
Lenaneo la Nicotinamide Mononucleotide (NMN)
Lenaneo la Nicotinamide Mononucleotide (NMN)
Sehlooho ka:

Ngaka Zeng

Mothehi-motheo, boetapele ba tsamaiso ea mantlha ea k'hamphani; PhD e amohetse Univesithing ea Fudan ka k'hemistri ea manyolo. Ho ba le boiphihlelo bo fetang lilemo tse robong ho chemistry ea tlhaho le moralo oa lithethefatsi; lipampiri tse ka bang 10 tsa lipatlisiso tse phatlalalitsoeng likoranteng tse nang le matla, tse nang le litokelo tse fetang tse hlano tsa China.

References

(1). Yao, Z., et al. (2017). Nicotinamide Mononucleotide e Thibela Ts'ebetso ea JNK ea ho Fokotsa Maloetse a Alzheimer.

(2). Yoshino, J., le al. (2011). Nicotinamide Mononucleotide, NAD (+) ea Bohlokoa, e Tšoara Pathophysiology ea Lijo le Lefu la Ts'oaetso Le Ts'oarelitsoeng ke Lilemo ho Litoeba. Cell Metabolism.

(3). Yamamoto, T., le al. (2014). Nicotinamide Mononucleotide, e bohareng ba NAD + Synthesis, E Sireletsa Pelo ho Ischemia le Reperfusion.

(4). Wang, Y., et al. (2018). NAD + Supplementation Normalizes Features of Alzheimer's Features and DNA Damage Responses in a New AD Mouse Model ka Tlhahiso ea DNA ea Tlhabollo.

(5). Keisuke, O., et al. (2019). Litlamorao tsa Phetoho ea NAD Metabolism Mathateng a Metabolic. Tlaleho ea Saense ea Biomedical.

(6). Leeto la ho hlahloba mohlala.

(7). Oleoylethanolamide (oea) - leqhubu la boloi la bophelo ba hau.

(8). Anandamide vs cbd: ke efe e molemo bakeng sa bophelo bo botle ba hau? Tsohle tseo o hlokang ho li tseba ka bona!

(9). Ntho e ngoe le e ngoe eo u hlokang ho e tseba ka nicotinamide riboside chloride.

(10). Lisebelisoa tsa Magnesium l-threonate: melemo, litekanyo le litla-morao.

(11). Palmitoylethanolamide (erekisi): melemo, litekanyetso li behoa, tšebeliso, tlatsetsa.

(12). Melemo e 6 e holimo ea bophelo bo botle ea litlatsetso tsa resveratrol.

(13). Melemo e 5 e holimo ea ho nka phosphatidylserine (ps).

(14). Melemo e 5 e holimo ea ho nka pyrroloquinoline quinone (pqq).

(15). Molemo ka ho fetisisa nootropic tlatsetsa ea alpha gpc.